| | 1268454-23-4 Basic information More.. |
| Product Name: | INK1117 | | Synonyms: | Methanone, [6-(2-aMino-5-benzoxazolyl)iMidazo[1,2-a]pyridin-3-yl]-4-Morpholinyl-;INK-1117 MLN1117;MLN1117;MLN1117 (INK1117);[6-(2-Amino-5-benzoxazolyl)imidazo[1,2-a]pyridin-3-yl]-4-morpholinylmethanone;[6-(2-amino-1,3-benzoxazol-5-yl)imidazo[1,2-a]pyridin-3-yl]-morpholin-4-ylmethanone;methyl 6-((5-((3-(trifluoromethyl)phenyl)carbamoyl)naphthalen-2-yl)oxy)pyrimidine-4-carboxylate;TAK-117(INK1117,MLN1117) | | CAS: | 1268454-23-4 | | MF: | C19H17N5O3 | | MW: | 363.37 | | EINECS: | | | Mol File: | 1268454-23-4.mol |  |
Use
INK1117 is an inhibitor of phosphoinositide 3-kinase α (PI3Kα) that is selective for p110α in vitro (IC50 = 15 nM for PI3Kα vs. >1 μM for other isoforms, as well as for mTOR) and in cells when used at 1 μM. It blocks signaling to Akt and inhibits growth of cancer cells harboring wild-type or mutated p110α. INK1117 does not interfere with B cell proliferation or NK cell maturation and survival.[Cayman Chemical]
- INK1117
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- US $1.00 / g
- 2019-12-20
- CAS:1268454-23-4
- Min. Order: 1g
- Purity: 99.99%
- Supply Ability: 2tons
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1268454-23-4
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