Valganciclovir hydrochloride
| 175865-59-5 Basic information More.. |
Product Name: | Valganciclovir hydrochloride | Synonyms: | L-Valine,2-[(2-aMino-1,6-dihydro-6-oxo-9H-purin-9-yl)Methoxy]-3-hydroxypropyl ester,hydrochloride (1:1);2-[(2-amino-6-oxo-6,9-dihydro-3H-purin-9-yl)methoxy]-3-hydroxypropyl (2S)-2-amino-3-methylbutanoate hydrochloride hydrate;L-Valine, 2-[(2-amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy]-3-hydroxypropyl ester, monohydrochloride hydrate;Valganciclovir hydrochloride hydrate;Rs 079070-194;Unii-4p3T9qf9nz;Valcyt;Valganciclovir hydrochlorid | CAS: | 175865-59-5 | MF: | C14H23ClN6O5 | MW: | 390.82 | EINECS: | 641-360-4 | Mol File: | 175865-59-5.mol | |
Use
Valganciclovir is the valyl ester prodrug of ganciclovir , an antiviral agent used for the treatment of HIV associated retinitis and for the prevention of post transplant cytomegalovirus (CMV) infections. Upon oral administration, intestinal and hepatic esterases rapidly convert valganciclovir to ganciclovir, which can inhibit viral DNA synthesis (IC50 = 0.95 μM) by targeting the CMV polymerase.
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175865-59-5
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