808-26-4 Basic information More..
Product Name:Sancycline
Synonyms:SANCYCLINE;(4S,4aS,5aR,12aS)-4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-1-11-dioxo-2-naphthacenecarboxamide;6-Demethyl-6-deoxytetracycline;Bonomycin;GS 2147;Norcycline;(4S,4aS,5aR,12aS)-4-(Dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydro-2-naphthacenecarboxamide;NSC-51812
CAS:808-26-4
MF:C21H22N2O7
MW:414.41
EINECS:
Mol File:808-26-4.mol
808-26-4

Use

Sancycline is a rare semi-synthetic tetracycline prepared by hydrogenolysis of the chloro and benzylic hydroxy moieties of declomycin, first reported in 1962. As the simplest of the early tetracyclines, sancycline was the first to be totally synthesised by Conover and co-workers. Like other tetracyclines, sancycline acts by reversibly binding to the 30S ribosomal subunit and inhibiting protein translation by blocking entry of aminoacyl-tRNA into the ribosome A site.

Sancycline manufacturers

  • Sancycline
  • US $2500.00 / g
  • 2024-03-27
  • CAS:808-26-4
  • Min. Order: 1g
  • Purity: 98
  • Supply Ability: 5 Kg
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