1191237-69-0 Basic information More..
Product Name:GS-441524
Synonyms:2-C-(4-AMINOPYRROLO[2,1-F][1,2,4]TRIAZIN-7-YL)-2,5-ANHYDRO-3,4-O-(1-METHYLETHYLIDENE)-D-ALTRONONITRI;D-Altrononitrile, 2-C-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-2,5-anhydro-;2-C-(4-Aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-2,5-anhydro-D-Altrononitrile;GS441525;(2R,3R,4S,5R)-2-(4-AMINOPYRROLO[2,1-F][1,2,4]TRIAZIN-7-YL)-3,4-DIHYDROXY-5-(HYDROXYMETHYL)TETRAHYDRO;GS-441524(EVO984);Remdesivir Impurity 6;S-441524
CAS:1191237-69-0
MF:C12H13N5O4
MW:291.26
EINECS:200-001-8
Mol File:1191237-69-0.mol
1191237-69-0

Use

GS-441524 is a nucleoside analogue antiviral drug which was developed by Gilead Sciences. It is the main plasma metabolite of the antiviral prodrug remdesivir, and has a half-life of around 24 hours in human patients. Remdesivir and GS-441524 were both found to be effective in vitro against feline coronavirus strains responsible for feline infectious peritonitis (FIP), a lethal systemic disease affecting domestic cats. Remdesivir was never tested in cats (though some vets now offer it[1]), but GS-441524 has been found to be effective treatment for FIP and is widely used despite no official FDA approval due to Gileads refusal to license this drug for veterinary use.

GS-441524 manufacturers

  • GS-441524
  • US $10.00 / ASSAYS
  • 2024-11-07
  • CAS:1191237-69-0
  • Min. Order: 1ASSAYS
  • Purity: 99%
  • Supply Ability: 10 ton
  • GS-441524
  • US $30.00 / mg
  • 2024-11-07
  • CAS:1191237-69-0
  • Min. Order:
  • Purity: 99.75%
  • Supply Ability: 10g
  • GS-441524
  • US $0.00 / G
  • 2024-11-07
  • CAS:1191237-69-0
  • Min. Order: 1G
  • Purity: 99%
  • Supply Ability: 20
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