| | 112137-89-0 Basic information More.. |
| Product Name: | Misoprostol Acid | | Synonyms: | MISOPROSTOL FREE ACID;(+/-)-15-DEOXY-[16RS]-16-HYDROXY-16-METHYLPROSTAGLANDIN E1;(11a,13E)-11,16-Dihydroxy-16-methyl-9-oxo-prost-13-en-1-oic Acid;(-15-Deoxy-(16RS)-16-hydroxy-16-methylprogestaglandin E;MISOPROSTOL ACID;(+/-)-15-Deoxy-(16RS)-16-hydroxy-16-methylprogestaglandin E1;Misoprostol free acid,(±)-15-Deoxy-(16RS)-16-hydroxy-16-methylprostaglandin E1;Misoprostol Acid (10 mg in 1 mL Methyl Acetate) | | CAS: | 112137-89-0 | | MF: | C21H36O5 | | MW: | 368.51 | | EINECS: | | | Mol File: | 112137-89-0.mol |  |
Use
Misoprostol Acid is a prostaglandin E1 analog with agonist activity mediated by EP2, EP3, and EP4 receptors. It has been shown to inhibit the formation of gastric lesions in rats (ED50 = 0.31 μg/kg), inhibit superoxide generation in human neutrophils (EC50 = 0.35 μM), and relax fetal rabbit ductus arteriosus (EC50 = 0.36 nM) in a concentration dependent manner. Misoprostol is commonly used in clinical medicine for the prevention of peptic ulcer disease. It has also been used in conjunction with mifepristone (RU-486; ) for the oral induction of first trimester abortion. Misoprostol contains a C-1 methyl ester and is readily absorbed and rapidly hydrolyzed in humans to the active free acid.
- Misoprostol acid
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- US $140.00-1170.00 / mg
- 2024-10-24
- CAS:112137-89-0
- Min. Order:
- Purity:
- Supply Ability: 10g
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112137-89-0
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