285570-60-7 Basic information More..
Product Name:Ac-DEVD-CMK
Synonyms:AC-ASP-GLU-VAL-ASP-CMK;AC-DEVD-CMK;CASPASE-3 INHIBITOR III;AC-ASP-GLU-VAL-ASP-CMK: AC-DEVD-CMK;CASPASE-3 INHIBITOR III ; AC-ASP-GLU-VAL-ASP-CMK;N-Acetyl-L-alpha-aspartyl-L-alpha-glutamyl-N-[(1S)-1-(carboxymethyl)-3-chloro-2-oxopropyl]-L-valinamide;Ac-Asp-Glu-Val-Asp-chloromethylketone;Ac-Asp-Glu-Val-Asp-chloromethylketone trifluoroacetate salt
CAS:285570-60-7
MF:C21H31ClN4O11
MW:550.94
EINECS:
Mol File:285570-60-7.mol
285570-60-7

Use

Ac-DEVD-CMK is a cell-permeable, and irreversible inhibitor of caspase-3 as well as caspase-6, -7, -8, and -10. It is commonly used at concentrations up to 100 μM to examine the role of caspase-3-dependent apoptosis in biological systems.

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