Quinupristin-dalfopristin
| 126602-89-9 Basic information More.. |
Product Name: | Quinupristin-dalfopristin | Synonyms: | Quinupristin-dalfopristin;SYNERCID;Quinupristin-Dalfopristin Mesylate coMplex;Synercid coMplex, Dalfopristin-Quinupristin coMplex;Mixture with quinupristin;Quinupristin-dalfopristin Mesylate complex
DISCONTINUED;Quinupristin dalfopristin mesylate;Quinipristine+ Dalfopristin Mesylate | CAS: | 126602-89-9 | MF: | C87H117N13O19S2 | MW: | 1713.09 | EINECS: | | Mol File: | 126602-89-9.mol | |
Use
Quinupristin-dalfopristin mesylate complex is a 70:30 (w/w) complex of two semi-synthetic analogues marketed as Synercid. Dalfopristin is a semisynthetic analogue of virginiamycin M, while quinupristin is a semi-synthetic analogue of virginiamycin B. To optimise stability, the compounds are presented as the mesylate salts with 10% sodium mesylate excess to provide a buffered aqueous solution. The complex is more hydrophobic than the naturally-occurring virginiamycin complex, with a readily ionisable group for generating a salt for improved solubility. There is little published data on the synthesis and biological activity of individual components of the complex, however the combination is a highly effective antibiotic, including activity against resistant strains.
|
126602-89-9
Recommend Suppliers |
|
Tag:
126602-89-9
|