91021-66-8 Basic information More..
Product Name:leucanicidin
Synonyms:leucanicidin;21-O-De(3-carboxy-1-oxo-2-propenyl)-2-demethyl-21-O-(6-deoxy-2-O-methyl-α-L-mannopyranosyl)-2-methoxy-24-methylhygrolidin;Oxacyclohexadeca-3,5,11,13-tetraen-2-one, 16-[(1S,2R,3S)-3-[(2R,4R,5S,6R)-4-[(6-deoxy-2-O-methyl-α-L-mannopyranosyl)oxy]tetrahydro-2-hydroxy-5-methyl-6-(1-methylethyl)-2H-pyran-2-yl]-2-hydroxy-1-methylbutyl]-8-hydroxy-3,15-dimethoxy-5,7,9,11-tetramethyl-, (3Z,5E,7R,8S,9S,11E,13E,15S,16R)-;(3Z,5E,7R,8S,9S,11E,13E,15S,16R)-16-[(1S,2R,3S)-3-[(2R,4R,5S,6R)-4-[(6-deoxy-2-O-methyl-α-L-mannopyranosyl)oxy]tetrahydro-2-hydroxy-5-methyl-6-(1-methylethyl)-2H-pyran-2-yl]-2-hydroxy-1-methylbutyl]-8-hydroxy-3,15-dimethoxy-5,7,9,11-tetramethyl-oxacyclohexadeca-3,5,11,13-tetraen-2-one
CAS:91021-66-8
MF:C42H70O13
MW:782.997
EINECS:
Mol File:91021-66-8.mol
91021-66-8

Use

Leucanicidin is a potent nematocide and insecticide belonging to the bafilomycin class. Lack of access to the pure metabolite has limited its investigation, however structural differences between leucanicidin and the bafilomycins offer scope for investigations into the use of V-ATPases as therapeutic targets.

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