7184-60-3 Basic information More..
Product Name:BORRELIDIN
Synonyms:2-(7-CYANO-8,16-DIHYDROXY-9,11,13,15-TETRAMETHYL-18-OXOOXACYCLOOCTADECA-4,6-DIEN-2-YL)-CYCLOPENTANECARBOXYLIC ACID;BORRELIDIN;BORRELIDINE;2-(7-Cyano-8,16-dihydroxy-9,11,13,15-tetramethyl-18-oxo-1-oxacyclooctadeca-4,6-dien-2-yl)cyclopentane-1-carboxylic acid;Aids128115;Aids-128115;Cyclopentanecarboxylic acid, 2-(7-cyano-8, 16-dihydroxy-9,11,13,15-tetramethyl-18-oxooxacyclooctadeca-4, 6-dien-2-yl)-;Quinquangulin K 031
CAS:7184-60-3
MF:C28H43NO6
MW:489.64
EINECS:
Mol File:7184-60-3.mol
7184-60-3

Use

Borrelidin is an unusual nitrile-containing metabolite isolated from Streptomyces. Originally discovered as active against Borrelia species, borrelidin has since found a role as a selective inhibitor of bacterial and eukaryal threonyl-tRNA synthetase. More recent research has found that borrelidin is a very potent angiogenesis inhibitor and induces apoptosis of the capillary tube-forming cells. Borrelidin is an important lead for antimalarial discovery, displaying activity against drug-resistant Plasmodia.

BORRELIDIN manufacturers

  • BORRELIDIN
  • US $1.00 / KG
  • 2020-03-12
  • CAS:7184-60-3
  • Min. Order: 1KG
  • Purity: 99.0%
  • Supply Ability: 100kg
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