| 148706-06-3 Basic information More.. |
Product Name: | 4-hydroxy Nonenal-d3 | Synonyms: | HNE-D3;(E)-4-HYDROXYNONENAL-D3;4-HNE-D3;(+/-)-4-HYDROXY-9,9,9,NON-2E-ENAL;4-HYDROXY NONENAL-D3;(E)-9,9,9-trideuterio-4-hydroxynon-2-enal;(±)-4-hydroxy-9,9,9-d3-non-2E-enal | CAS: | 148706-06-3 | MF: | C9H13D3O2 | MW: | 159.24 | EINECS: | | Mol File: | Mol File | ![148706-06-3](/StructureFile/ChemBookStructure9/GIF/CB1167997.gif) |
Use
4-hydroxy Nonenal-d3 (4-HNF-d3) contains three deuterium atoms at the terminal methyl position. It is intended for use as an internal standard for the quantification of 4-HNE by GC- or LC-mass spectrometry. 4-HNE is a lipid peroxidation product derived from oxidized ω-6 polyunsaturated fatty acids such as arachidonic acid. 4-HNE is widely used as a marker of lipid peroxidation. It exhibits various biological activities such as cytotoxicity, growth inhibiting activity, genotoxicity, and chemotactic activity. 4-HNE inhibits pro-oxidant-induced Ca2+ release from mitochondria at 10-50 μM.
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148706-06-3
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