95740-26-4 Basic information More..
Product Name:(2'S)-2'-Deoxy-2'-fluoro-5-ethynyluridine
Synonyms:(2'S)-2'-Deoxy-2'-fluoro-5-ethynyluridine;1-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-5-ethynyluracil;F-ara-EdU;2,4(1H,3H)-Pyrimidinedione, 1-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-5-ethynyl-;1-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-5-ethynyluracil
CAS:95740-26-4
MF:C11H11FN2O5
MW:270.22
EINECS:
Mol File:95740-26-4.mol
95740-26-4

Use

(2′S)-2′-Deoxy-2′-fluoro-5-ethynyluridine is a commonly used probe for DNA synthesis in vivo as it exhibits minimal impact on genome function in diverse tissue types. (2′S)-2′-deoxy-2′-fluoro-5-ethynyluridine is also ideally suited for metabolic DNA labeling when prolonged cell survival and undisturbed cell cycle progression are necessary, such as for pulse-chase experiments aimed at “birth dating” DNA in vivo.

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