(Trifluoromethyl)trimethylsilane
| 81290-20-2 Basic information More.. |
Product Name: | (Trifluoromethyl)trimethylsilane | Synonyms: | TriMethyl(trifluoroMethyl)silane solution 0.5 M in THF;(TrifluoroMethyl)triMethylsilane SynonyMs TriMethyl(trifluoroMethyl)silane;(Trimethylsilyl)trifluoromethane
Ruppert-Prakash Reagent;Reagents, Ruppert's;TriMethylsilyl(trifluoroMethyl)silane;TriMethyl(trifluoroMethyl)sila;TriMethyl(trifluoroMethyl)silane 99%;TriMethyl(trifluoroMethyl)silane solution ~2.0 M in THF | CAS: | 81290-20-2 | MF: | C4H9F3Si | MW: | 142.2 | EINECS: | | Mol File: | 81290-20-2.mol | |
Use
(Trifluoromethyl)trimethylsilane (TMSCF3) is versatile reagent for trifluoromethylation, such as transition-metal-catalyzed reaction, miscellaneous trifluoromethylation, and addition to carbonyl and imine groups. These reactions are extremely useful approaches in the pharmaceutical and agrochemical industry, because they enhance metabolic stability (metabolic blocking) and alter the compound properties (liphophilicity, binding selectivity).
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81290-20-2
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81290-20-2
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