| | 74639-40-0 Basic information More.. |
| Product Name: | Docarpamine | | Synonyms: | Docarpamine;Carbonic acid, 4-[2-[[(2S)-2-(acetylamino)-4-(methylthio)-1-oxobutyl]amino]ethyl]-1,2-phenylene diethyl ester;Carbonic acid, 4-[2-[[2-(acetylamino)-4-(methylthio)-1-oxobutyl]amino]ethyl]-1,2-phenylene diethyl ester, (S)-;TA 870;Tanadopa;(S)-2-(Acetylamino)-N-[3,4-bis(ethoxycarbonyloxy)phenethyl]-4-(methylthio)butanamide;3,4-Bis[(ethoxycarbonyl)oxy]-N-(N-acetyl-L-methionyl)benzeneethanamine;TA-8704 | | CAS: | 74639-40-0 | | MF: | C21H30N2O8S | | MW: | 470.54 | | EINECS: | | | Mol File: | 74639-40-0.mol |  |
Use
Docarpamine is a cardiostimulant with diuretic activity launched in Japan for the
treatment of circulatory insufficiency. It is an orally effective peripheral dopamine
prodrug that is well absorbed from the gastrointestinal tract and converted to
dopamine in vivo, which exerts renal vasodilatory and natriuretic effects by
activating renal dopamine (DA1) receptors, and a positive inotropic effect by
activating cardiac β1-receptors. It has been reported to be effective in treating
patients with acute heart failure, shock and acute renal failure.
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74639-40-0
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