1140909-48-3 Basic information More..
Product Name:Cabozantinib Malate
Synonyms:1-N-[4-(6,7-dimethoxyquinolin-4-yl)oxyphenyl]-1-N'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide,(2S)-2-hydroxybutanedioic acid;Smalate;XL184(S)-malate;N-(2-{[(3R)-1-(4-CHLOROBENZYL)-3-PYRROLIDINYL]AMINO}-2-OXOETHYL)-3-(TRIFLUOROMETHYL)BENZAMIDE HYDROCHLORIDE (1:1);(2S)-2-Hydroxybutanedioic acid compd. with N-[4-[(6,7-dimethoxy-4-quinolinyl)oxy]phenyl]-N'-(4-fluorophenyl)-1,1-cyclopropanedicarboxamide (1:1);Cabozantinib (S)-malate;Cabozantinib L-Malate Salt;N-[4-[(6,7-DiMethoxy-4-quinolinyl)oxy]phenyl]-N'-(4-fluorophenyl)-1,1-cyclopropanedicarboxaMide (2S)-
CAS:1140909-48-3
MF:C32H30FN3O10
MW:635.6
EINECS:691-711-0
Mol File:1140909-48-3.mol
1140909-48-3

Use

Cabozantinib malate is the malate of Cabozantinib, a potent VEGFR2 inhibitor with IC50 of 0.035 nM and also inhibits c-Met, Ret, Kit, Flt-1/3/4, Tie2, and AXL with IC50 of 1.3 nM, 4 nM, 4.6 nM, 12 nM/11.3 nM/6 nM, 14.3 nM and 7 nM, respectively.

Cabozantinib Malate manufacturers

  • Cabozantinib Malate
  • US $0.00 / kg
  • 2024-11-23
  • CAS:1140909-48-3
  • Min. Order: 1kg
  • Purity: 99% HPLC
  • Supply Ability: 1000kg
  • Cabozantinib S-Malate
  • US $0.00-0.00 / kg
  • 2024-11-22
  • CAS:1140909-48-3
  • Min. Order: 1kg
  • Purity: 99%, Single impurity<0.1
  • Supply Ability: 1 ton
  • Cabozantinib S-malate
  • US $40.00-73.00 / mg
  • 2024-11-19
  • CAS:1140909-48-3
  • Min. Order:
  • Purity: 98.87%
  • Supply Ability: 10g
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