37134-40-0 Basic information More..
Product Name:BicozaMycin benzoate, FR 2054
Synonyms:BicozaMycin benzoate, FR 2054;BicycloMycin benzoate;Bicyclomycin benzoate,FR 2054;FR2054;Bicyclomycin, 3'-benzoate (9CI);(2S,3S)-2,3-dihydroxy-3-((1S,6R)-6-hydroxy-5-methylene-8,10-dioxo-2-oxa-7,9-diazabicyclo[4.2.2]decan-1-yl)-2-methylpropyl benzoate
CAS:37134-40-0
MF:C19H22N2O8
MW:406.39
EINECS:
Mol File:37134-40-0.mol
37134-40-0

Use

BicozaMycin benzoate, FR 2054 is a polar metabolite first isolated from Streptomyces sapporonensis in 1972, with activity against Gram negative bacteria. The selective Gram negative profile of bicyclomycin is rare among Streptomyces metabolites, and in an effort to overcome its poor in vivo absorption, the benzoate ester was prepared by reaction with the more exposed primary alcohol. BicozaMycin benzoate, FR 2054 benzoate has limited use as a veterinary antibiotic.

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