| | 18048-95-8 Basic information More.. |
| Product Name: | MethaMphenicol | | Synonyms: | Corynecin III;MethaMphenicol;N-[(1RS,2RS)-2-hydroxy-1-hydroxymethyl-2-(4-nitro-phenyl)-ethyl]-isobutyramide;Propanamide, N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]-2-methyl- | | CAS: | 18048-95-8 | | MF: | C13H18N2O5 | | MW: | 282.29 | | EINECS: | | | Mol File: | 18048-95-8.mol |  |
Use
Corynecin III (methamphenicol) is a member of a naturally-occurring complex of chloramphenicol-like acyl nitrophenylpropylamines isolated from Corynebacterium hydrocarboclastus in 1972. Corynecin III is active against Gram positive and Gram negative bacteria. Although less potent than chloramphenicol, corynecin III shows a similar species selectivity. Corynecin III was used as a bioisostere of chloroamphenicol to examine the binding relationship of chloramphenicols to DraE virulence factor.
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18048-95-8
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