| | 939960-34-6 Basic information More.. |
| Product Name: | OrfaMide A | | Synonyms: | OrfaMide A;L-Valine, N-(3-hydroxy-1-oxotetradecyl)-L-leucyl-D-α-glutamyl-D-allothreonyl-D-alloisoleucyl-L-leucyl-D-seryl-L-leucyl-L-leucyl-D-seryl-, (10→3)-lactone | | CAS: | 939960-34-6 | | MF: | C64H114N10O17 | | MW: | 1295.67 | | EINECS: | | | Mol File: | 939960-34-6.mol |  |
Use
Orfamide A is the major component of a family of cyclic lipopeptides produced by Pseudomonas fluorescens, reported in 2007. The orfamides were discovered by employing genomic analysis with an isotope-guided fractionation to identify metabolites produced by orphan gene clusters containing non-ribosomal peptide synthetases. Orfamide A has received scant investigation of its bioprofile but appears to be a selective antifungal agent. Uniquely, orfamide A lyses zoospores of the oomycete, Phytophthora ramorum, the cause of sudden oak death. Orfamide A has a profound effect on the swarming motility of bacteria on agar surfaces.
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939960-34-6
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