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Product Name:ophiobolin C
Synonyms:ophiobolin C;3-Hydroxy-5-oxoophiobola-7,19-dien-25-al;Zizanin A;Dicyclopenta[a,d]cyclooctene-4-carboxaldehyde, 7-[(1S)-1,5-dimethyl-4-hexen-1-yl]-1,2,3,3a,6,6a,7,8,9,9a,10,10a-dodecahydro-1-hydroxy-1,9a-dimethyl-3-oxo-, (1R,3aS,6aS,7R,9aR,10aS)-
CAS:19022-51-6
MF:C25H38O3
MW:386.57
EINECS:
Mol File:19022-51-6.mol
19022-51-6

Use

Ophiobolin C is a member of the ophiobolin class of phytotoxic metabolites produced by many species of the genus Bipolaris. Ophiobolin C inhibits human CCR5 binding to the envelope protein gp120 and CD4 that mediates HIV-1 entry into cells. Blockade of this binding was considered by scientists at Merck as a potential new mode of action for the treatment of HIV-1 infection.

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