402849-27-8 Basic information More..
Product Name:4-Chloro-2-(4-chlorobenzoyl)-1-(4-Methoxyphenyl)hydrazide Benzoic Acid
Synonyms:Indapamide EP Impurity F;Indomethacin EP Impurity F;Indometacin Impurity 14;Indomethacin Impurity 6(Indomethacin EP Impurity F);Indometacin EP Impurity F;Indomethacin Impurity F;Indometacin (Indomethacin) EP Impurity F;Indomethacin impurity 5/Indomethacin EP Impurity F/2-(4-Chlorobenzoyl)-1-(4-methoxyphenyl)hydrazide-4-chloro-benzoic acid
CAS:402849-27-8
MF:C21H16Cl2N2O3
MW:415.27
EINECS:
Mol File:402849-27-8.mol
402849-27-8

Use

4-Chloro-2-(4-chlorobenzoyl)-1-(4-Methoxyphenyl)hydrazide Benzoic Acid is an impurity of the anti-inflammatory drug indomnethacin (I641000). Indomethacin inhibits cyclooxygenase (IC50=0.1uM) selectively over liposygenases (IC50=100uM for 5-,12- and 15-LO). A clinically useful NAISD.

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