147536-97-8 Basic information More..
Product Name:Bosentan
Synonyms:2’-bipyrimidin)-4-yl)-enoxy)(;benzenesulfonamide,4-(1,1-dimethylethyl)-n-(6-(2-hydroxyethoxy)-5-(2-methoxyph;ro47-0203;4-(tert-Butyl)-N-(6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-[2,2'-bipyrimidin]-4-yl)benzenesulf;Bosentan impurity;Bosentan 13C6;ro47-0203/039;BOSENTAN
CAS:147536-97-8
MF:C27H29N5O6S
MW:551.61
EINECS:643-099-1
Mol File:147536-97-8.mol
147536-97-8

Use

Bosentan is a mixed endothelin receptor antagonist. Used as a vasodilator. Antihypertensive. Bosentan is an orally administered, nonselective ET-1 receptor antagonist blocking ETA and ETB receptors and is approved for the treatment of patients with PAH. Following oral administration, bosentan attains peak plasma concentrations in approximately 3 hours, with an absolute bioavailability of approximately 50%. Food has no clinically relevant effect on its absorption recommended doses.

Bosentan manufacturers

  • Bosentan
  • US $32.00-74.00 / mg
  • 2024-11-11
  • CAS:147536-97-8
  • Min. Order:
  • Purity: 99.8%
  • Supply Ability: 10g
  • Bosentan
  • US $15.00-10.00 / KG
  • 2021-07-13
  • CAS:147536-97-8
  • Min. Order: 1KG
  • Purity: 99%+ HPLC
  • Supply Ability: Monthly supply of 1 ton
  • Bosentan
  • US $15.00-10.00 / KG
  • 2021-07-09
  • CAS:147536-97-8
  • Min. Order: 1KG
  • Purity: 99%+ HPLC
  • Supply Ability: Monthly supply of 1 ton
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