| | 72263-05-9 Basic information More.. |
| Product Name: | CONGLOBATIN | | Synonyms: | (3E,5R,7S,8S,11E,13R,15S,16S)-3,5,7,11,13,15-Hexamethyl-8,16-bis(5-oxazolylmethyl)-1,9-dioxacyclohexadeca-3,11-diene-2,10-dione;FW-04-806;CONGLOBATIN;Conglobatin, >=99%;1,9-Dioxacyclohexadeca-3,11-diene-2,10-dione, 3,5,7,11,13,15-hexamethyl-8,16-bis(5-oxazolylmethyl)-, (3E,5R,7S,8S,11E,13R,15S,16S)-;Conglobactin | | CAS: | 72263-05-9 | | MF: | C28H38N2O6 | | MW: | 498.61 | | EINECS: | | | Mol File: | 72263-05-9.mol |  |
Use
Isolated from Streptomyces conglobatus, conglobatin has a unusual, dimeric, macrolide dilactone structure with pendant oxazole groups. Conglobatin exhibits an IC50 of 0.63 μg/ml in a NFAT-dependant transcription assay. No toxicity was observed at doses up to 1000 mg/kg when administered to mice either orally or interperitoneally.
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72263-05-9
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