| | 151271-53-3 Basic information More.. |
| Product Name: | UK 1 | | Synonyms: | UK 1;UK 1 (cytotoxin);2'-(2-Hydroxyphenyl)-[2,4'-bibenzoxazole]-4-carboxylic acid methyl ester;[2,4'-Bibenzoxazole]-4-carboxylic acid, 2'-(2-hydroxyphenyl)-, methyl ester | | CAS: | 151271-53-3 | | MF: | C22H14N2O5 | | MW: | 386.36 | | EINECS: | | | Mol File: | 151271-53-3.mol |  |
Use
UK-1 is an unusual bis-benzoxazole metabolite isolated from a species of Streptomyces. UK-1 exhibits good antitumor activity but is devoid of antimicrobial activity. UK-1 acts as a magnesium ion-dependent DNA binding agent and inhibitor of human topoisomerase II.
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151271-53-3
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