| | 102676-31-3 Basic information More.. |
| Product Name: | FADROZOLE HYDROCHLORIDE | | Synonyms: | FADROZOLE HYDROCHLORIDE;CGS-16949A;Fadrazole;D02451;Fadrozole hydrochloride (usan);4-(5,6,7,8-Tetrahydroimidazo[1,5-a]pyridin-5-yl)benzonitrile hydrochloride;4-(5,6,7,8-TETRAHYDROIMIDAZO[1,5-A]PYRIDIN-5-YL)BENZONITRILE(WXC09920);Fadrozole HCl | | CAS: | 102676-31-3 | | MF: | C14H13N3.ClH | | MW: | 259.739 | | EINECS: | | | Mol File: | 102676-31-3.mol |  |
Use
Fadrozole hydrochloride is a non-steroidal imidazole derivative launched for the treatment of post-menopausal breast cancer. Fadrozole is a potent and
specific aromatase inhibitor with neither androgenic nor estrogenic activities due to its
structural novelty. Fadrozole exerts its action by coordinating with the iron of the
porphyrin nucleus, presumably through the imidazole moiety. This strong binding
competes with the binding of molecular oxygen to iron and reversibly inactivates the
enzyme. An excellent clinical response rate has been reported for fadrozole with no
significant side effects.
- Fadrozole hydrochloride
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- US $42.00-128.00 / mg
- 2024-11-09
- CAS:102676-31-3
- Min. Order:
- Purity: ≥95%
- Supply Ability: 10g
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102676-31-3
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