| trans-Ned-19-d8 Basic information More.. |
Product Name: | trans-Ned-19-d8 | Synonyms: | (1R,3S)-1-[3-[[4-(2-Fluorophenyl)-1-(piperazinyl-d8)]Methyl]-4-Methoxyphenyl]-2,3,4,9-tetrahydro-1H-Pyrido[3,4-b]indole-3-carboxylic Acid;trans-Ned-19-d8 | CAS: | | MF: | C30H30FN4O3 | MW: | 513.5826032 | EINECS: | | Mol File: | Mol File | ![trans-Ned-19-d8](/CAS/20140608/GIF/CB42558488.gif) |
Use
trans-Ned-19-d8, a cell permeable and potent nicotinic acid adenine dinucleotide phosphate (NAADP) antagonist. trans-Ned-19 inhibits NAADP-mediated Ca2+ release (IC50 = 6 nM) and also inhibits [ 32P]NAADP binding (IC50 = 0.4 nM). trans-Ned-19 can be used as a chemical proble since it fluorescentey labels NAADP receptors in intact cells.
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trans-Ned-19-d8
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