KRN 633

286370-15-8 Basic information More..

Product Name:	KRN 633
Synonyms:	KRN 633;N-[2-Chloro-4-[(6,7-dimethoxy-4-quinazolinyl)oxy]phenyl]-N'-propylurea;1-(2-chloro-4-(6,7-diMethoxyquinazolin-4-yloxy)phenyl)-3-propylurea;N-[2-Chloro-4-[(6,7-dimethoxy-4-quinazolinyl)oxy]phenyl]-N'-propylurea KRN633;VEGFR Tyrosine Kinase Inhibitor III, KRN633;KRN 633;KRN-633;CS-463;KRN633; KRN-633; KRN 633
CAS:	286370-15-8
MF:	C20H21ClN4O4
MW:	416.86
EINECS:
Mol File:	286370-15-8.mol

Use

KRN 633 is an ATP-competitive inhibitor of VEGFR1/2/3 with IC50 of 170 nM/160 nM/125 nM and also inhibits PDGFRα/β with IC50 of 965 nM/9850 nM.

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