134523-03-8 Basic information More..
Product Name:Atorvastatin calcium
Synonyms:ATORVASTATIN CALCIUM;(3R,5R)-7-(2-(4-FLUOROPHENYL)-5-ISOPROPYL-3-PHENYL-4-(PHENYLCARBAMOYL)-1H-PYRROL-1-YL)-3,5-DIHYDROXYHEPTANOIC ACID CALCIUM;(3R,5R)-7-(2-(4-fluorophenyl)-5-isopropyl-3-;(R,dR)-2-(4-Fluorophenyl)-,d-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoic Acid Calcium;3S,5S-Atorvastatin Calcium;Bis[(3R,5R)-3,5-dihydroxy-7-[2-(1-methylethyl)-3-[(phenylamino)carbonyl]-4-phenyl-5-(4-fluorophenyl)-1H-pyrrol-1-yl]heptanoic acid]calcium salt;Bis[(3R,5R)-7-[2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrole-1-yl]-3,5-dihydroxyheptanoic acid] calcium salt;Bis[(3R,5R)-7-[2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-phenylcarbamoyl-1-pyrrolyl]-3,5-dihydroxyheptanoic acid] calcium salt
CAS:134523-03-8
MF:C33H37CaFN2O5
MW:600.74
EINECS:200-659-6
Mol File:134523-03-8.mol
134523-03-8

Use

Atorvastatin calcium[trade name: Lipitor] is a statin-class medication used mainly for lowering the lipid as well as preventing the event associated with cardiovascular disease[1, 2]. Being similar to other kinds of statins, atorvastatin take effects by inhibiting HMG-CoA reductase, an enzyme found in liver tissue that plays a key role in production of cholesterol in the body. Atorvastatin acts primarily in the liver. Decreased hepatic cholesterol levels further increases hepatic uptake of cholesterol and reduces plasma cholesterol levels[3, 4]. Lipitor, since 1996, has become the worlds best-selling medication to that point[5, 6], with more than US$125 billion in sales over approximately 14.5 years. As of 2016, in the UK, atorvastatin costs about 2 per month[5].

Atorvastatin calcium manufacturers

  • Atorvastatin calcium
  • US $0.00 / Kg/Drum
  • 2024-08-31
  • CAS:134523-03-8
  • Min. Order: 1KG
  • Purity: 98%-102%; USP
  • Supply Ability: 500KGS
  • Atorvastatin calcium
  • US $3600.00 / Kg/Bag
  • 2024-08-30
  • CAS:134523-03-8
  • Min. Order: 1KG
  • Purity: 99%
  • Supply Ability: 1T
  • Atorvastatin calcium
  • US $500.00-300.00 / kg
  • 2024-08-30
  • CAS:134523-03-8
  • Min. Order: 1kg
  • Purity: 99%
  • Supply Ability: 5000
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