| | 202590-98-5 Basic information More.. |
| Product Name: | OTX015 | | Synonyms: | OTX015(OTX-015);6H-Thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetamide, 4-(4-chlorophenyl)-N-(4-hydroxyphenyl)-2,3,9-trimethyl-, (6S)-;MK 8628;MK8628;MK-8628;OTX015;OTX 015;OTX-015;2-((6S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)-N-(4-hydroxyphenyl)acetamide;OTX 015 | | CAS: | 202590-98-5 | | MF: | C25H22ClN5O2S | | MW: | 491.99 | | EINECS: | | | Mol File: | 202590-98-5.mol |  |
Use
OTX015 inhibits the binding of BRD2, BRD3, and BRD4 to AcH4 with IC50 ranging from 92 to 112 nM, and inhibits the growth of a variety of human cancer cell lines with GI50 ranging from 60 to 200 nM. OTX015 results in rapid down-regulation of c-MYC expression, and show the synergistic anti-proliferative effects in combination with ALK inhibitors in ALKpos ALCL cell lines.
- OTX015
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- US $0.00 / mg
- 2024-07-25
- CAS:202590-98-5
- Min. Order: 1mg
- Purity: 98%min
- Supply Ability: 50mg
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202590-98-5
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