| 91-80-5 Basic information More.. |
Product Name: | METHAPYRILENE | Synonyms: | N-(2-Pyridyl)-N-(2-thienylmethyl)-N',N'-dimethylethylenediamine;2-dimethylaminoethyl-(2-pyridyl)-(2-thienylmethyl)amine;N',N'-dimethyl-N-pyridin-2-yl-N-(thiophen-2-ylmethyl)ethane-1,2-diamine;1,2-Ethanediamine, N,N-dimethyl-N'-2-pyridinyl-N'-(2-thienylmethyl)-;2-((2-(dimethylamino)ethyl)-2-thenylamino)-pyridin;2-((2-(dimethylamino)ethyl)-2-thenylamino)pyridine;2-((2-(dimethylamino)ethyl)-2-thienylamino)pyridine;2-[(2-dimethyl-aminoethyl)-2-thenylamino]pyridine | CAS: | 91-80-5 | MF: | C14H19N3S | MW: | 261.38576 | EINECS: | 2020998 | Mol File: | 91-80-5.mol | |
Use
Methapyrilene, an antihistamine with moderate sedative activity,
was introduced in 1947 for the treatment of various allergic conditions and was
subsequently incorporated in many over-the-counter sleeping aids. In the early
1970s it was identified as a carcinogen in rats and, although there was no direct
evidence that it constitutes a health hazard to man, it was withdrawn in many
countries.
(Reference: (WHODI) WHO Drug Information, 2, 4, 1979)
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91-80-5
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