| | 95734-82-0 Basic information More.. |
| Product Name: | Nedaplatin | | Synonyms: | (glycolato-o,o')diammineplatinum(ii);cis-diammine(glycolato)platinum(ii);NEDAPLATIN;254-s;o(sup2))-diammine(hydroxyacetato(2-)-o(sup1(sp-4-3)-platinu;Nedaplait;o(sup 2))- diammine(hydroxyacetato(2-)-o(sup 1 (sp-4-3)-platinu (glycolato-o,o')diammineplatinum(ii) 254-s cis-diammine(glycolato)platinum(ii) nedaplatin nsc 375101d;2,2-diaMino-1,3-dioxa-2-platinacyclopentan-4-one | | CAS: | 95734-82-0 | | MF: | C2H6N2O3Pt | | MW: | 301.17 | | EINECS: | | | Mol File: | 95734-82-0.mol |  |
Use
Nedaplatin, a novel second generation platinum complex, was marketed
in Japan for the treatment of a variety of cancers including: head and neck, small-cell
and non-small cell lung, oesophageal, prostatic, testicular, ovarian, cervical, bladder,
and uterine cancers. Platinum anticancer agents, prototyped by cisplatin, have been
reported to be hydrolyzed to the mono- or diaquated species of diamine platinum which
react with nucleophilic sites on DNA to cause intrastrand and interstrand crosslinks and
DNA-protein crosslinks, which result in cytotoxicity. Nedaplatin was reportedly more
active than cisplatin against several solid tumors while sharing less nephro- and
gastrointestinal toxicity to cisplatin in viva The minimal renal toxicity displayed by
nedaplatin allows its use in patients with deteriorated renal function.
- Nedaplatin
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- US $0.00 / g
- 2024-09-14
- CAS:95734-82-0
- Min. Order: 1g
- Purity: 98%-102%
- Supply Ability: 100g
- Nedaplatin
-
- US $15.00-10.00 / KG
- 2021-07-13
- CAS:95734-82-0
- Min. Order: 1KG
- Purity: 99%+ HPLC
- Supply Ability: Monthly supply of 1 ton
- Nedaplatin
-
- US $15.00-10.00 / KG
- 2021-07-09
- CAS:95734-82-0
- Min. Order: 1KG
- Purity: 99%+ HPLC
- Supply Ability: Monthly supply of 1 ton
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95734-82-0
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