| | 1393-48-2 Basic information More.. |
| Product Name: | THIOSTREPTON | | Synonyms: | Thiostrepton (200 mg);BryaMycin, Thiactin, AlaninaMide, X 146, A 8506, 6761-31;Thiostrepton, froM StreptoMyces sp.;x146;THIOSTREPTON;Alaninamide, L-threonyl-(4S)-2-(1Z)-1-amino-1-propenyl-4,5-dihydro-4-thiazolecarbonyl-2-(1S,2S,3R)-1-amino-2,3-dihydroxy-2-methylbutyl-4-thiazolecarbonyl-2-(5R,6S)-6-2-(1S,2R)-1-amino-2-hydroxypropyl-4-thiazolyl-5-N-(7R,8S)-2-carboxy-7,8-dihydro-8-hydroxy;THIOSTREPTION;thiostrepton from streptomyces azureus | | CAS: | 1393-48-2 | | MF: | C72H85N19O18S5 | | MW: | 1664.89 | | EINECS: | 215-734-9 | | Mol File: | 1393-48-2.mol |  |
Use
Thiostrepton is a macrocyclic antibiotic incorporating thiazoles and other atypical amino acids. Patented in 1961, thiostrepton has been used as an antibiotic and acts by binding to ribosomes to prevent the binding of the EF-G elongation factor and GTP to the 50S ribosomal subunit. Thiostrepton is an inducer of tipA, a gene that controls the bacterial transcription regulators, and TipAL and TipAS, that are central regulators in multidrug resistance. Thiostrepton is closely related to siomycin, a recently discovered inhibitor of oncogenic transcription factor, FoxM1.
- THIOSTREPTON
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- US $0.00 / KG
- 2023-08-30
- CAS:1393-48-2
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 50000KG/month
- Thiostrepton
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- US $15.00-10.00 / KG
- 2021-07-13
- CAS:1393-48-2
- Min. Order: 1KG
- Purity: 99%+ HPLC
- Supply Ability: Monthly supply of 1 ton
- Thiostrepton
-
- US $15.00-10.00 / KG
- 2021-07-10
- CAS:1393-48-2
- Min. Order: 1KG
- Purity: 99%+ HPLC
- Supply Ability: Monthly supply of 1 ton
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1393-48-2
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