| | 37517-30-9 Basic information More.. |
| Product Name: | Acebutolol | | Synonyms: | (.+/-.)-3'-Acetyl-4'-[2-hydroxy-3-(1-methylethylamino)propoxy]butyranilide;(.+/-.)-3'-Acetyl-4'-[2-hydroxy-3-(isopropylamino)propoxy]butyranilide;(.+/-.)-N-(3-Acetyl-4-(2-hydroxy-3-((1-methylethyl)amino)propoxy)phenyl)butanamide;1-(2-Acetyl-4-n-butyramidophenoxy)-2-hydroxy-3-isopropylaminopropane;3'-Acetyl-4'-(2-hydroxy-3-(isopropylamino)propoxy)butyranilide;5'-Butyramido-2'-(2-hydroxy-3-isopropylaminopropoxy)acetophenone;Butanamide, N-[3-acetyl-4-[2-hydroxy-3-[(1-methylethyl)amino]propoxy]phenyl]-, (.+/-.)-;dl-Acebutolol | | CAS: | 37517-30-9 | | MF: | C18H28N2O4 | | MW: | 336.43 | | EINECS: | 253-539-0 | | Mol File: | 37517-30-9.mol |  |
Use
Acebutolol is one of the very few β-blockers whosemetabolite plays a significant role in its pharmacological actions.This drug is absorbed well from the gastrointestinaltract, but it undergoes extensive first-pass metabolic conversionto diacetolol by hydrolytic conversion of the amidegroup to the amine, followed by acetylation of the amine. After oral administration, plasma levels of diacetololare higher than those of acebutolol. Diacetolol is also aselective β1-blocker with partial agonistic activity; it has littlemembrane-stabilizing activity. It has a longer half-life (8–12hours) than the parent drug and is excreted by the kidneys.
- Acebutolol
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- US $1.00 / ASSAYS
- 2020-01-09
- CAS:37517-30-9
- Min. Order: 1ASSAYS
- Purity: 85.0-99.8%
- Supply Ability: 20tons
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37517-30-9
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