136470-78-5 Basic information More..
Product Name:Abacavir
Synonyms:1592u89;[(1s,4r)-4-[2-amino-6-(cyclopropylamino)purin-9-yl]-1-cyclopent-2-enyl]methanol;[(1S,4R)-4-(2-AMINO-6-CYCLOPROPYLAMINO-PURIN-9-YL)-CYCLOPENT-2-ENYL]-METHANOL;2-Cyclopentene-1-methanol, 4-[2-amino-6-(cyclopropylamino)-9H-purin-9-yl]-, (1S,4R)-;2-Cyclopentene-1-methanol, 4-[2-amino-6-(cyclopropylamino)-9H-purin-9-yl]-, (1S-cis)-;(+/-)-4-[2-amino-6-(cyclopropylamino)-9h-purin-9-yl]-2-cyclopentene-1-methanol;Abacavir;Abacavir (see A105000)
CAS:136470-78-5
MF:C14H18N6O
MW:286.33
EINECS:620-487-9
Mol File:136470-78-5.mol
136470-78-5

Use

Abacavir is a nucleoside reverse transcriptase inhibitorNRTI that has been approved for use in combination therapiesfor the treatment of HIV and AIDS. Once in the tissues,it is metabolized by stepwise phosphorylation to themonophosphate, diphosphate, and triphosphate. Abacavir ishighly bioavailable (>75%) and is effective by the oralroute. It penetrates the blood-brain barrier efficiently.Abacavir has been reported to produce life-threatening hypersensitivityreactions in some patients.

Abacavir manufacturers

  • Abacavir
  • US $0.00 / G
  • 2024-10-14
  • CAS:136470-78-5
  • Min. Order: 50G
  • Purity: 98%min
  • Supply Ability: 30kg/month
  • Abacavir
  • US $5.00-0.10 / KG
  • 2024-04-16
  • CAS:136470-78-5
  • Min. Order: 1KG
  • Purity: 99%
  • Supply Ability: g-kg-tons, free sample is available
  • Abacavir
  • US $0.00 / KG
  • 2024-03-16
  • CAS:136470-78-5
  • Min. Order: 100g
  • Purity: 98%+
  • Supply Ability: 100kg
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