| | 58-40-2 Basic information More.. |
| Product Name: | Promazine | | Synonyms: | PHENOTHIAZINE,10-(3-(DIMETHYLAMINO)PROPYL)-;N,N-Dimethyl-3-(10H-phenothiazin-10-yl)propan-1-amine;dimethyl(3-phenothiazin-10-ylpropyl)amine;A-145;RP-3276;Wy-1094;Promazine;N,N-dimethyl-3-phenothiazin-10-yl-propan-1-amine | | CAS: | 58-40-2 | | MF: | C17H20N2S | | MW: | 284.4191 | | EINECS: | 2003820 | | Mol File: | 58-40-2.mol |  |
Use
Promazine, 10-[3-(dimethylamino) propyl-(phenothiazine monohydrochloride (Sparine), was introducedinto antipsychotic therapy after its 2-chloro-substitutedrelative. The 2H-substituent vis-à-vis the 2Clsubstituent gives a milligram potency decrease as an antipsychotic,as encompassed in Gordon’s rule. Tendency toEPS is also lessened, which may be significant, especially ifit is decreased less than antipsychotic potency.
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58-40-2
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