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Product Name:methylnaltrexone
Synonyms:methylnaltrexone;17-(Cyclopropylmethyl)-4,5α-epoxy-3-methoxy-14-hydroxymorphinan-6-one;3-Methoxy-14-hydroxy-17-(cyclopropylmethyl)-4,5α-epoxymorphinan-6-one;3-O-Methylnaltrexone;4,5α-Epoxy-3-methoxy-14β-hydroxy-17-(cyclopropylmethyl)morphinan-6-one;Naltrexone methyl ether;17-(Cyclopropylmethyl)-4,5alpha-epoxy-3,14-dihydroxy-17-methyl-6-oxomorphinanium;17-(Cyclopropylmethyl)-4,5-epoxy-3,14-dihydroxymorphinanium-6-one
CAS:83387-25-1
MF:C21H26NO4+
MW:356.43544
EINECS:
Mol File:83387-25-1.mol
83387-25-1

Use

Methylnaltrexone (Relistor) is the methylated, quaternaryform of naltrexone . The permanently chargednitrogen prevents the drug from crossing the blood-brainbarrier. Thus, it only acts as an antagonist at peripheralopioid receptors. Relistor was approved in April 2008 totreat opioid-induced constipation in patients receiving palliativecare. It is administered as a SC injection once everyother day.

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