| | 114-86-3 Basic information More.. |
| Product Name: | Phenformin | | Synonyms: | (phenylethyl)biguanide;1-phenethyl-biguanid;azucaps;beta-PEBG;beta-Phenethybiguanide;beta-Phenethylbiguanide;Biguanide, 1-phenethyl-;cronoformin | | CAS: | 114-86-3 | | MF: | C10H15N5 | | MW: | 205.26 | | EINECS: | 204-057-4 | | Mol File: | 114-86-3.mol |  |
Use
Phenformin, a biguanide with oral hypoglycaemic activity, was
introduced in 1957 for the management of diabetes mellitus. By 1970 its use had
been associated with incidences of lactic acidosis and by 1976 clinical studies had
conclusively demonstrated that the hazards of phenformin treatment outweighed
the benefits. Preparations containing phenformin were withdrawn in several
countries and their use restricted in others. Elsewhere, however, proprietary
preparations containing this drug may remain available. The related biguanide,
buformin, has been also associated with lactic acidosis and has been subjected to
similar restrictions as phenformin, whereas there is some evidence that metformin
is less liable to induce lactic acidosis.
(Reference: (WHODI) WHO Drug Information, 2, 4, 1977)
- Phenformin
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- US $999.00-666.00 / g
- 2024-11-03
- CAS:114-86-3
- Min. Order: 1g
- Purity: 99%
- Supply Ability: 5000
- Phenformin
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- US $149.00-218.00 / mg
- 2024-10-31
- CAS:114-86-3
- Min. Order:
- Purity: 97.07%
- Supply Ability: 10g
- Phenformin
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- US $10.50 / KG
- 2024-10-11
- CAS:114-86-3
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 10 ton
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114-86-3
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