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114177-14-9 Basic information More..
Product Name:MilbeMycin A3 OxiMe
Synonyms:MilbeMycin A3 OxiMe;5-OxoMilbeMycin A3 oxiMe;Milbemycin Impurity 10(Milbemycin A3 Oxime);5-ketomilbemycin A3 5-oxime;Milbemycin B, 5-demethoxy-28-deoxy-6,28-epoxy-5-(hydroxyimino)-25-methyl-, (6R,25R)-;Milbemite Impurity 2
CAS:114177-14-9
MF:C31H43NO7
MW:541.68
EINECS:
Mol File:114177-14-9.mol
114177-14-9

Use

Milbemycin A3 oxime is a semi-synthetic macrocyclic lactone prepared by the oxidation and oximation of milbemycin A3. Milbemycin A3 oxime is the minor component (~30%) in the commercial product milbemycin oxime, marketed for endo- and exo-parasite infections. Like the other milbemycin/avermectins, milbemycin A3 oxime acts by opening glutamate sensitive chloride channels in neurons of invertebrates leading to paralysis by hyperpolarisation of these cells and signal transfer blocking.

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