1799753-84-6 Basic information More..
Product Name:BAY-876
Synonyms:N4-[1-[(4-cyanophenyl)methyl]-5-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl]-7-fluoro-2,4-Quinolinedicarboxamide;BAY-876;N4-(1-(4-cyanobenzyl)-5-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl)-7-fluoroquinoline-2,4-dicarboxamide;CS-2442;BAY876;BAY 876;BAY-876 >=98% (HPLC);2,4-Quinolinedicarboxamide, N4-[1-[(4-cyanophenyl)methyl]-5-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl]-7-fluoro-;Inhibitor,metabolism,transporter,ovarian,BAY876,BAY 876,glycolytic,cancer,Glucose transporter,glucose,inhibit,BAY-876,orally,GLUT
CAS:1799753-84-6
MF:C24H16F4N6O2
MW:496.42
EINECS:
Mol File:1799753-84-6.mol
1799753-84-6

Use

BAY-876 is a potent, highly selective, cell-permeable inhibitor of glucose transporter GLUT1. It had an IC50 value of 2 nM in vitro and inhibited glucose uptake by Hela-MaTu cells with an IC50 value of 3.2 nM. BAY-876 was at least 130-fold selective for GLUT1 relative to GLUT2, GLUT3, GLUT4 and a panel of 18 kinases and 68 proteins.BAY-588 is used as a negative control and is available from Sigma.

BAY-876 manufacturers

  • BAY-876
  • US $1.00 / KG
  • 2019-12-27
  • CAS:1799753-84-6
  • Min. Order: 1KG
  • Purity: 97%-99.9%
  • Supply Ability: 100kg
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