91700-92-4 Basic information More..
Product Name:herbimycin C
Synonyms:herbimycin C;(15R)-17-Demethoxy-15-methoxygeldanamycin;(15R)-17-Demethoxy-15β-methoxygeldanamycin;Antibiotic TAN-420D;TAN-420D;Geldanamycin, 17-demethoxy-15-methoxy-, (15R)-
CAS:91700-92-4
MF:C29H40N2O9
MW:560.64
EINECS:
Mol File:91700-92-4.mol
91700-92-4

Use

Herbimycin C is a minor analogue of the herbimycin complex isolated from Streptomyces hygroscopicus. Herbimycin C possesses potent antitumor activity and converts Rous sarcoma virus-infected rat kidney cells into normal cells. Until now limited access has restricted a full investigation of the properties of herbimycin C. Research on related metabolites, herbimycin A and geldanamycin, has stimulated intensive interest in this class as selective antitumor agents and for prolonging the viability of tissue-cultured cells and organs.

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