| | 41708-72-9 Basic information More.. |
| Product Name: | TOCAINIDE | | Synonyms: | TOCAINIDE;2-amino-2',6'-propionoxylidide;2-amino-n-(2,6-dimethylphenyl)-propanamid;6'-propionoxylidide, 2-amino-2;alanyl-2,6-xylidide;Astra W-36095;W-36095;2-Amino-N-(2,6-dimethylphenyl)propanamide | | CAS: | 41708-72-9 | | MF: | C11H16N2O | | MW: | 192.26 | | EINECS: | 255-505-0 | | Mol File: | 41708-72-9.mol |  |
Use
Tocainide, an antidysrhythmic agent, was introduced in 1981 for
the treatment of ventricular dysrhythmias. By 1984 its use was associated with
cases of agranulocytosis, aplastic anaemia and thrombocytopenia, some of which
were fatal. This led some regulatory authorities to restrict the indications for its
use. The major manufacturer has subsequently restricted its use on a worldwide
basis to the treatment of symptomatic ventricular dysrhythmias not responding to
other therapy, or when other therapy is contraindicated.
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41708-72-9
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