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Product Name:DMOG
Synonyms:N-(METHOXYOXOACETYL)-GLYCINE METHYL ESTER;DIMETHYLOXALLYL GLYCINE;N-[(Methoxycarbonyl)Methyl]oxaMic Acid Methyl Ester;DiMethyloxaloylglycine (DMOG);METHYL 2-(2-METHOXY-2-OXOETHYLAMINO)-2-OXOACETATE;N-(2-Methoxy-2-oxoacetyl)glycine methyl ester;DMOG Dimethyloxalylglycine N-[(Methoxycarbonyl)methyl]oxamic acid methyl ester;DMOG, >=98%
CAS:89464-63-1
MF:C6H9NO5
MW:175.14
EINECS:200-256-5
Mol File:89464-63-1.mol
89464-63-1

Use

DMOG is a cell permeable prolyl-4-hydroxylase inhibitor which upregulates HIF activity. HIF activation stimulates angiogenesis in several different models (1nM). DMOG also inhibits FIH (factor inhibiting HIF), an asparaginyl hydroxylase, which enhances the HIF response. It is active in vivo and attenuates myocardial injury in a rabbit ischemia reperfusion model (20mg/Kg).

DMOG manufacturers

  • DMOG
  • US $5.00 / KG
  • 2019-09-04
  • CAS:89464-63-1
  • Min. Order: 1KG
  • Purity: 99%
  • Supply Ability: 1ton
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