81129-83-1 Basic information More..
Product Name:Cilastatin sodium
Synonyms:Cilastatine;Cilastatin sodium;Sodium 7-(2-amino-2-carboxy-ethyl)sulfanyl-2-(2,2-dimethylcyclopropyl)carbonylamino-hept-2-enoate;Sodium hydrogen 7-[(2-amino-2-carboxylatoethyl)thio]-2-[[(2,2-dimethylcyclopropyl)carbonyl]amino]hept-2-enoate;Sodium Cilastatin;[R-[R*,S*-(Z)]]-7-[(2-Amino-2-carboxyethyl)thio]-2-[[(2,2-dimethylcyclopropyl)carbonyl]amino]-2-heptenoic acid monosodium salt;(Z)-7-[(R)-2-Amino-2-carboxyethylthio]-2-[(S)-2,2-dimethylcyclopropylcarbonylamino]-2-heptenoic acid 1-sodium salt;(2Z)-7-[[(2R)-2-Amino-2-carboxyethyl]thio]-2-[[[(1S)-2,2-dimethylcyclopropyl]carbonyl]amino]-2-heptenoicacidsodiumsalt
CAS:81129-83-1
MF:C16H25N2O5S.Na
MW:380.44
EINECS:279-694-4
Mol File:81129-83-1.mol
81129-83-1

Use

ChEBI: The monosodium salt of cilastatin. It is an inhibitor of dehydropeptidase I (membrane dipeptidase, 3.4.13.19), an enzyme found in the brush border of renal tubes and responsible for degrading the antibiotic imipenem. Cilastatin sodium is therefore administ red with imipenem to prolong the antibacterial effect of the latter by preventing its renal metabolism to microbiologically inactive and potentially nephrotoxic products.

Cilastatin sodium manufacturers

  • Cilastatin sodium
  • US $0.00 / KG
  • 2024-12-13
  • CAS:81129-83-1
  • Min. Order: 1KG
  • Purity: 98%min
  • Supply Ability: 30tons/month
  • Cilastatin sodium
  • US $0.00 / mg
  • 2024-10-28
  • CAS:81129-83-1
  • Min. Order:
  • Purity:
  • Supply Ability: 10g
  • Cilastatin Sodium
  • US $0.00 / kg
  • 2024-05-07
  • CAS:81129-83-1
  • Min. Order: 1kg
  • Purity: 99%
  • Supply Ability: 10000kg
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