| | 897383-62-9 Basic information More.. |
| Product Name: | AST-1306 | | Synonyms: | AST-1306;ALS 1306;N-[4-[[3-Chloro-4-[(3-fluorobenzyl)oxy]phenyl]amino]quinazolin-6-yl]acrylamide;N-[4-[[3-Chloro-4-[(3-fluorophenyl)methoxy]phenyl]amino]-6-quinazolinyl]-2-propenamide;Allitinib (AST1306);Allitinib;CS-590;N-(4-(4-(3-fluorobenzyloxy)-3-chlorophenylamino)quinazolin-6-yl)acrylamide | | CAS: | 897383-62-9 | | MF: | C24H18ClFN4O2 | | MW: | 448.88 | | EINECS: | | | Mol File: | 897383-62-9.mol |  |
Use
AST-1306 is a selective irreversible inhibitor of the epidermal growth factor receptor (EGFR) 1 and 2. Studies show that AST-1306 inhibited the enzymatic activities of wild-type EGF) and ErbB2 as well
as EGFR resistant mutant in both cell-free and cell-based systems. AST-1306 was more effective in inhibiting tumors with ErbB2-overexpressing cells than EGFR-overexpressing tumor.
- AST-1306
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- US $9.80 / KG
- 2020-01-13
- CAS:897383-62-9
- Min. Order: 1g
- Purity: ≥99%
- Supply Ability: 100kg
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897383-62-9
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