1187594-09-7 Basic information More..
Product Name:Baricitinib
Synonyms:1-(Ethylsulfonyl)-3-[4-(7H-pyrrolo[2,3-d]pyriMidin-4-yl)-1H-pyrazol-1-yl]-3-azetidineacetonitrile;Baricitinib;INCB 028050;LY 3009104;BARICITINIB;INCB28050;LY3009104;Baricitinib (LY3009104);2-(3-(4-(3H-Pyrrolo[2,3-d]pyriMidin-4-yl)-1H-pyrazol-1-yl)-1-(ethylsulfonyl)azetidin-3-yl)acetonitrile;Baricitinib/INCB 028050/LY3009104
CAS:1187594-09-7
MF:C16H17N7O2S
MW:371.42
EINECS:691-421-4
Mol File:1187594-09-7.mol
1187594-09-7

Use

Baricitinib represents a selective inhibitor of JAKs with excellent potency and selectivity for JAK2 (IC50=5.7nM) and JAK1 (IC50=5.9nM), and less potency and selectivity for JAK3 (IC50 >400nM), or TYK2 (IC50=53nM). Although baricitinib potently inhibits JAKs, it does not significantly inhibit (<30% inhibition) a broad panel of 26 other kinases when tested at 200nM.

Baricitinib manufacturers

  • Baricitinib
  • US $2.00 / kg
  • 2024-12-12
  • CAS:1187594-09-7
  • Min. Order: 1kg
  • Purity: 99%
  • Supply Ability: 1200KG/M
  • Baricitinib
  • US $80.00-60.00 / KG
  • 2024-12-12
  • CAS:1187594-09-7
  • Min. Order: 1KG
  • Purity: 99%
  • Supply Ability: 500
  • Baricitinib
  • US $100.00-80.00 / KG
  • 2024-12-12
  • CAS:1187594-09-7
  • Min. Order: 1KG
  • Purity: 99.9%
  • Supply Ability: 1000
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