| | 1092538-80-1 Basic information More.. |
| Product Name: | SAR131675 | | Synonyms: | 2-amino-1-ethyl-7-(3-hydroxy-4-methoxy-3-methylbut-1-ynyl)-N-methyl-4-oxo-1,8-naphthyridine-3-carboxamide | | CAS: | 1092538-80-1 | | MF: | C18H22N4O4 | | MW: | 358.39 | | EINECS: | | | Mol File: | 1092538-80-1.mol |  |
Use
SAR131675 is a potent and selective VEGFR-3 inhibitor. It inhibited VEGFR-3 tyrosine kinase activity and VEGFR-3 autophosphorylation in HEK cells. SAR131675 also dose dependently inhibited the prolife
ration of primary human lymphatic cells, induced by the VEGFR-3 ligands VEGFC and VEGFD.
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1092538-80-1
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