| | 136817-59-9 Basic information More.. |
| Product Name: | DELAVIRDINE | | Synonyms: | U-90152;DELAVIRDINE;1-(3-((1-Methylethyl)amino)-2-pyridinyl)-4-((5-((methylsulfonyl)amino)-1H-indol-2-yl)carbonyl)piperazine;147221-93-0 (Mesylate);2-(4-(5-Methanesulfonamido-1H-indol-2-ylcarbonyl)-1-piperazinyl)-N-(1-methylethyl)-3-pyridinamine;Bhap-U 90152;Unii-dol5F9jd3e;Delavirdine & Delavirdine Mesylate | | CAS: | 136817-59-9 | | MF: | C22H28N6O3S | | MW: | 456.56 | | EINECS: | | | Mol File: | 136817-59-9.mol |  |
Use
Delavirdine (Rescriptor) must be used with at least twoadditional antiretroviral agents to treat HIV-1 infections.The oral absorption of delavirdine is rapid, and peakplasma concentrations develop in 1 hour. Extensive metabolismoccurs in the liver by CYP isozyme 3A (CYP3A) orpossibly CYP2D6. Bioavailability is 85%. Unlike nevirapine,which is 48% protein bound, delavirdine is more than98% protein bound. The half-life is 2 to 11 hours, andelimination is 44% in feces, 51% in urine, and less than 5%unchanged in urine. Delavirdine induces its own metabolism.Oral dosage forms are supplied as a 200-mg capsuleand a 100-mg tablet.
- Delavirdine
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- US $80.00 / kg
- 2024-08-12
- CAS:136817-59-9
- Min. Order: 1kg
- Purity: 0.99
- Supply Ability: 1000000tons
- DELAVIRDINE
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- US $8.00-2.00 / kg
- 2024-04-24
- CAS:136817-59-9
- Min. Order: 1kg
- Purity: 99%
- Supply Ability: g-kg-tons, free sample is available
- DELAVIRDINE USP/EP/BP
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- US $1.10 / g
- 2021-07-16
- CAS:136817-59-9
- Min. Order: 1g
- Purity: 99.9%
- Supply Ability: 100 Tons Min
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136817-59-9
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