BLASTICIDIN S HYDROCHLORIDE
| 3513-03-9 Basic information More.. |
Product Name: | BLASTICIDIN S HYDROCHLORIDE | Synonyms: | BLASTICIDINE S HYDROCHLORIDE;BLASTICIDIN S HYDROCHLORIDE;BLASTICIDIN S, HYDROCHLORIDE, STREPTOMYCES GRISEOCHROMOGENES;Blasticidine S hydrochloride,Blasticidin S;(S)-4-[[3-amino-5-[(aminoiminomethyl)methylamino]-1-oxopentyl]amino]-1-(4-amino-2-oxo-1(2H)-pyrimidinyl)-1,2,3,4-tetradeoxy-β-D-erythro-Hex-2-enopyranuronic acid,monohydrochloride;Blasticidine S HCl;Blasticidine S hydrochloride solution;Blasticidine S hydrochloride solution,1000ppm | CAS: | 3513-03-9 | MF: | C17H27ClN8O5 | MW: | 458.9 | EINECS: | | Mol File: | 3513-03-9.mol | |
Use
Blasticidin S hydrochloride is a salt of blasticidin S, an amphoteric nucleoside produced by several species of Streptomyces, first reported in the late 1950s. Blasticidin S hydrochloride was originally isolated by acetone precipitation. For historical reasons only the salt has been routinely available to researchers. Both the salt and free base are freely water soluble. Blasticidin S is an antifungal agent with particularly potent activity against the rice pathogen, Piricularia oryzae, for which it was used commercially for some time in Japan. Blasticidin S inhibits protein synthesis and is active against bacteria, tumor cell lines and nematodes. More recently, blasticidin S has been used as a marker for strain manipulations.
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3513-03-9
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3513-03-9
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