| | 93413-62-8 Basic information More.. |
| Product Name: | O-Desmethylvenlafaxine | | Synonyms: | O-DESMETHYL VENLAFAXINE-D10;DL-O-Desmethylvenlafaxin;4-[2-(Dimethylamino)-1-(1-hydroxycyclohexyl)ethyl]phenol;O-Desmethylvenlafaxine;Desvenlafaxine(O-Desnethylvenfaxine);1-[1-(4-Hydroxyphenyl)-2-dimethylaminoethyl]cyclohexanol;4-[1-(1-Hydroxycyclohexyl)-2-(dimethylamino)ethyl]phenol;Desmethylvenlafaxine | | CAS: | 93413-62-8 | | MF: | C16H25NO2 | | MW: | 263.38 | | EINECS: | 700-516-2 | | Mol File: | 93413-62-8.mol |  |
Use
Desvenlafaxine is a new member of the SNRI class of antidepressants.
It is marketed as an extended release tablet for once-daily oral treatment
of MDD in adult patients. Desvenlafaxine (O-desmethylvenlafaxine) is
the major active metabolite of the previously marketed antidepressant
venlafaxine (Effexor). Similar to venlafaxine, desvenlafaxine is a more
potent inhibitor of serotonin and norepinephrine reuptake (IC50＝47 and
531 nM, respectively) than that of dopamine (62% inhibition at 100 mM)
in in vitro studies. It does not have significant in vitro affinity for other
neurotransmitter reporters such as a1-adrenergic, H1-histaminergic,
or muscarine-cholinergic receptors. Desvenlafaxine is marketed as a
racemic mixture. Specific pharmacological properties of the enantiomers
of desvenlafaxine have not been reported.
- O-Desmethylvenlafaxine
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- US $0.00-0.00 / KG
- 2021-07-20
- CAS:93413-62-8
- Min. Order: 5mg
- Purity: 99% HPLC
- Supply Ability: 2000tons
- O-Desmethylvenlafaxine
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- US $2.00 / kg
- 2019-07-06
- CAS:93413-62-8
- Min. Order: 1kg
- Purity: 99%
- Supply Ability: 100kg
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93413-62-8
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