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Product Name:SINEFUNGIN
Synonyms:6,7,8,9-hexadeoxy-yl)-5;6,9-diamino-1-(6-amino-9h-purin-9-d-glycero-alpha-l-talo-decofuranuronicaci;6,9-diamino-1-(6-amino-9h-purin-9-yl)-1,5,6,7,8,9-hexadeoxydecofuranuronica;compound57926;rp32232;SINEFUNGIN;5'-DEOXY-5'-(1,4-DIAMINO-4-CARBOXYBUTYL)ADENOSINE;ADENOSYLORNITHINE
CAS:58944-73-3
MF:C15H23N7O5
MW:381.39
EINECS:637-385-5
Mol File:58944-73-3.mol
58944-73-3

Use

Sinefungin, a polar nucleoside antifungal active with broad biological activity, was isolated from a number of species of Streptomyces in the early 1970s. Sinefungin acts by inhibiting a wide range of methyltransferases, including the methylation of bases in DNA and RNA which alters cytosine deamination and gene expression. Sinefungin is widely used as a bioprobe to block methyltransferase-dependent pathways.

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