66-76-2 Basic information More..
Product Name:DICUMAROL
Synonyms:BIS-HYDROXYCOUMARIN;BISCUMAROL;DICUMAROL;2H-1-Benzopyran-2-one, 3,3'-methylenebis[4-hydroxy-;3,3’-methyleen-bis(4-hydroxy-cumarine);3,3’-methylen-bis(4-hydroxy-cumarin);3,3’-methylenebis(4-hydroxy-1,2-benzopyrone);3,3’-methylenebis(4-hydroxy-2h-1-benzopyran-2-on
CAS:66-76-2
MF:C19H12O6
MW:336.3
EINECS:200-632-9
Mol File:66-76-2.mol
66-76-2

Use

Dicumarol is used alone or as an adjunct to heparin in theprophylaxis and treatment of intravascular clotting. It is usedin postoperative thrombophlebitis, pulmonary embolus, acuteembolic and thrombotic occlusion of peripheral arteries, andrecurrent idiopathic thrombophlebitis. It has no effect on analready-formed embolus but may prevent further intravascularclotting. Because the outcome of acute coronary thrombosisdepends largely on extension of the clot and formation ofmural thrombi in the heart chambers, with subsequent embolization,dicumarol has been used in this condition. It hasalso been administered to arrest impending gangrene afterfrostbite. The dose, after determination of the prothrombinclotting time, is 25 to 200 mg, depending on the size and thecondition of the patient. The drug is given orally in the formof capsules or tablets. On the second day and thereafter, itmay be given in amounts sufficient to maintain the prothrombinclotting time at about 30 seconds. If hemorrhages shouldoccur, a dosage of 50 to 100 mg of menadione sodium bisulfiteis injected, supplemented by a blood transfusion.

DICUMAROL manufacturers

  • DICUMAROL USP/EP/BP
  • US $1.10 / g
  • 2021-08-05
  • CAS:66-76-2
  • Min. Order: 1g
  • Purity: 99.9%
  • Supply Ability: 100 Tons min
  • DICUMAROL
  • US $1.00 / KG
  • 2019-07-14
  • CAS:66-76-2
  • Min. Order: 1KG
  • Purity: 99%
  • Supply Ability: 25kg
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