(4R,5S)-(+)-4-i-Propyl-5-(3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooctyl)-2-oxazolidinone

Use

(4R,5S)-(+)-4-i-Propyl-5-(3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooctyl)-2-oxazolidinone is a chiral fluorous support for conventional and high-throughput organic synthesis. Induces high stereoselectivity in aldol reactions, cycloadditions, conjugate additions and a variety of other reactions of N-acyl derivatives. The fluorous chain permits rapid and efficient isolation of products by solid phase extraction, using only minimal amounts of common solvents.Class of catalytic ligands which when used with a reducing agent, exhibit enantioselectivity in the reduction of a wide range of substrates.